PhD - Projects

  • Development and longitudinal assessment of small airway physiology in healthy infants and infants with cystic fibrosis using the multiple-breath washout technique: Are the measured MBW outcomes different between healthy infants and infants with CF and are the different measurement setups comparable? (Oestreich, Ramsey)
  • Translation and validation of functional lung MRI as a clinical tool in paediatric lung disease: Is the functional MP-MRI useful to monitor paediatric lung disease and foremost early CF lung disease? (Willers, Latzin)
  • Combination of functional imaging and detailed longitudinal lung function assessment to describe lung development in preterm children: Which long-term effects has prematurity on lung development? Funded by SNF. (Salem, Yammine)
  • Prediction of survival in patients with cystic fibrosis: Is LCI predictive of survival in patients with cystic fibrosis? Funded by Vertex Pharmaceuticals. (Kurz, Singer)
  • Novel ways to assess lung function in cystic fibrosis: How to improve and combine novel CF lung function measures in longitudinal studies? (Kentgens, Latzin)
  • Longterm course of clinically measured LCI in children with CF: Define the course of clinically measured LCI over 7 years and assess influencing factors as well as the natural test variability and minimal clinically important difference. Funded by SNF and Vertex Pharmaceuticals (Frauchiger, Ramsey, Latzin)
  • Effects of vaping on pulmonary health in teenagers: Comparison of biomarkers of lung health (respiratory symptoms assessed through questionnaires, lung function measures (Lung Clearance Index) and structure (Magnetic Resonance Imaging), oxidative stress in urines, and immunological state of nasal epithelia between vaping and non-vaping teenagers. Funded by the Bangerter Foundation (Jakob, Fuchs, Auer).
  • The significance of environmental and genetic factors in the development and function of the immune system: Which are the environmental and genetic factors, that are impacting the development of the immune system and can be used as risk factors or biomarkers to predict atopic diseases at the age of six? (Soti, Fuchs)
  • Effects of Electronic Nicotine Delivery Systems on pulmonary health in teenagers. The e-BILD study. (Jakob, Fuchs)
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